Description
Hilton Pharma Artem DS Plus Tablet is an antimalarial medication used for the treatment of malaria. Here are the key details regarding this specific product:
Product Overview
- Name: Artem DS Plus Tablet
- Manufacturer: Hilton Pharma
- Dosage: 40 mg Artemether and 240 mg Lumefantrine
- Pack Size: 8 tablets
Uses
Artem DS Plus is indicated for:
- Treatment of Malaria: Specifically effective against uncomplicated malaria caused by Plasmodium falciparum, including cases resistant to chloroquine. It is also used for severe malaria, including cerebral malaria.
Mechanism of Action
- Artemether: A derivative of artemisinin, it acts rapidly against the malaria parasite by generating free radicals that damage the parasite.
- Lumefantrine: Works by inhibiting the beta-hematin formation, which is essential for the parasite’s survival, thereby enhancing the effectiveness of artemether.
Dosage and Administration
- Typical Dosage: The recommended dosage for adults and children over 12 years is typically 4 tablets (160 mg/960 mg) taken as a single dose on the first day, followed by 2 tablets (80 mg/480 mg) twice daily for the next two days.
- Administration: It should be taken with food to enhance absorption.
Side Effects
Common side effects may include:
- Nausea
- Vomiting
- Abdominal pain
- Dizziness
- Fatigue
Serious side effects can occur but are rare, including arrhythmias or severe allergic reactions.
Precautions
- Contraindicated in patients with a history of arrhythmias, bradycardia, or congestive heart failure.
- Use with caution in patients with electrolyte disturbances or those taking other medications that prolong the QT interval.
- Not recommended during pregnancy or lactation due to potential risks.
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