Flagyl Injection, 100ml Vial

Description

Flagyl Injection is a sterile intravenous formulation containing Metronidazole, an antibiotic effective against various anaerobic bacterial infections. Here are the key details:

Key Details:

• Generic Name: Metronidazole
• Dosage Form: Injection
• Strength: 500 mg per 100 ml
• Pack Size: 100 ml vial

Composition:

Each vial contains:

• 500 mg Metronidazole
• Other excipients include sodium chloride, dibasic sodium phosphate, and citric acid to maintain stability and isotonicity.

Indications:

Flagyl Injection is primarily used for:

• Treatment of serious infections caused by susceptible anaerobic bacteria.
• Prophylaxis in surgical procedures, particularly colorectal surgeries, to prevent postoperative infections.

Dosage and Administration:

• Loading Dose: 15 mg/kg infused over one hour (approximately 1 g for a 70 kg adult).
• Maintenance Dose: 7.5 mg/kg every six hours after the loading dose.

Important Considerations:

• Metronidazole has been associated with potential side effects such as nausea, vomiting, and neurological symptoms (e.g., peripheral neuropathy).
• It should be used cautiously in patients with a history of blood dyscrasias or those with severe hepatic impairment.
• The use of metronidazole is contraindicated in certain conditions due to its carcinogenic potential observed in animal studies.